Microglial Morphological Changes in the Molecular Layer of Dentate Gyrus After Ophthalmic Instillation of Toxoplasma Gondii Tachyzoites
Year: 2023
Type: article
Abstract: INTRODUCTION: Microglial cells react to insults with multiple morphofunctional phenotypes in neurological diseases. We looked for surveillant and reactive microglia, using three-dimensional (3D) microscopic reconstructions, after ocular infection by Toxoplasma gondii. We used a series of anatomical brain sections from previous study and tested the hypothesis that microglial reactivity would be induced in the limbic system, whose areas affected by the pathogen have been associated with behavioral changes.
Source: IBRO Neuroscience Reports
Authors: Luma Guerreiro, Gabrielly Soares, Jhonnathan De Oliveira, Gabriel De Menezes, Alexa De Assis, Diego Miranda, Felipe Franco, Sanderson Araújo, Ediclei Do Carmo, Rafaela Morais, Emanuel Da Costa, Julia Da Silva, Patrick Pereira, José Antônio Junior, Cristovam Diniz, Daniel Diniz
Language: English
Subfield: Neurology
Field: Neuroscience
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $1,500
OpenAlex ID: W4388364132