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Astrocytes Adjust the Dynamic Range of Cortical Network Activity to Control Modality-specific Sensory Information Processing

Year: 2023

Type: article

Abstract: The extraction of behaviouraly relevant sensory information at cortical levels is only possible due to the interaction of parallel neuronal circuitries. However, it is now clear that glial cells, especially astrocytes, form a second network capable to set the basis by which neuronal output is defined in time and space. Here, we used a combination of in/ex vivo electrophysiology, behaviour and genetic tools to explored how changes in the spatiotemporal patterns of astrocytic networks alter the integration and processing of sensory information at cellular, network and behavioral level.

Source: IBRO Neuroscience Reports

DOI: 10.1016/j.ibneur.2023.08.430

Authors: Claudia Miguel-Quesada, Salvador Herrera-Perez, Marta Zaforas, Justin Lines, Elena Fernández-López, Elena Alonso-Calviño, Maria Ardaya, Federico N. Soria, Alfonso Araque, Juan Aguilar, Juliana Rosa

Institutions: Hospital Nacional de Parapléjicos, University of Minnesota, Achucarro Basque Center for Neuroscience, Servicio de Salud de Castilla La Mancha

Language: English

Topic: Neuroscience and Neuropharmacology Research

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $1,500

OpenAlex ID: W4388364215

FWCI:

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