Work

Alkaline Fibrin Hydrogel and Tol-51 Sulfoglycolipid Inhibitor Supporting Axonal Growth by Aldynoglia Cells

Year: 2023

Type: article

Abstract: Traumatic spinal cord injury has complex pathophysiological events that begin after the trauma; an important event is formation of fibroglial scar by fibroblasts and reactive astrocytes. This causes inhibition of axonal growth by activated astroglial cells; for example, through the secretion of inhibitory molecules, such as chondroitin sulfate proteoglycans. In this project, the goal was to analyse the properties of modified fibrin glue as support for neural cell growth and differentiation at different concentrations.

Source: IBRO Neuroscience Reports

DOI: 10.1016/j.ibneur.2023.08.239

Authors: Alejandro Arriero-Cabañero, Vinnitsa Buzoianu-Anguiano, Alfonso Fernandez-Mayoralas, Ernesto Doncel-Pérez

Institutions: Hospital Nacional de Parapléjicos, Consejo Superior de Investigaciones Científicas, Instituto de Química Orgánica General

Language: English

Topic: Nerve injury and regeneration

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,500