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Tamoxifen Reduces Mechanical Allodynia Ater Spinal Cord Injury in Female Rats

Year: 2023
Type: article
Abstract: Spinal cord injury (SCI) causes chronic pain in 60% of individuals. Plasticity after SCI within the rostral, epicenter, and caudal penumbra initiate a cellular-molecular interplay, which has been proposed as a re-wiring mechanism leading to central neuropathic pain (CNP). The initial trauma triggers harmful, pro-apoptotic and pro-inflammatory, mechanisms among other cellular events. To treat SCI, we must identify a multifactorial agent that can influence the immediate and long-term consequences of trauma.
Language: English
Field: Medicine
Open Access status: gold
Estimated APC paid: $1,500
OpenAlex ID: W4388364869
FWCI:
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Related to: 10