Cutaneous Kaposi Sarcoma Indicative of HIV/AIDS Infection: Two Cases Report and Review of the Literature at Regional Hospital Centre of Niamey (Niger)
Year: 2023
Type: article
Study design: Case Report
Abstract: Kaposi sarcoma (KS), first described in 1872 by the dermatologist Moricz Cohen Kaposi, is the most common neoplasm of people living with HIV today. Kaposi Sarcoma remains the most common cancer in people living with HIV in sub-Saharan Africa, where it causes significant morbidity and mortality. We report the case of two patients from Niger, aged 43 and 65 years old, who consulted unit of HIV care the Niamey Regional Hospital for an exploration of skin lesions in a context of altered general condition including significant weight loss. The clinical diagnosis of Kaposi's disease on a background of HIV immunodeficiency was retained. The clinical lesions were infiltrating cuteneous bluish nodular skin lesions with macules located on the legs, forearm and abdomen. The treatment consisted in putting the patients on high antiretroviral treatment followed by courses of chemotherapy. The combination of high antiretroviral therapy was started with TDF-3TC-EFV one tablet daily at bedtime. These study show the clinical polymorphism, the diagnostic delay and the treatment including polychemotherapy and antiretroviral drugs. Early diagnosis and detection of lesions could improve management and the prognosis of this disease.
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4389688385