Electrocardiographic and Echocardiographic Abnormalities, and Cirrhotic Cardiomyopathy in Patients Hospitalized at the Campus University Hospital (Lomé)
Year: 2023
Type: article
Study design: Observational Study
Abstract: Cirrhotic cardiomyopathy is a constellation of structural and functional cardiac abnormalities in patients with liver cirrhosis, apart from any underlying cardiac pathology, which potentially worsens the prognosis of these patients. The objectives of this study were to describe electrocardiographic and echocardiographic abnormalities in cirrhotic patients and estimate the prevalence of cirrhotic cardiomyopathy. This is a cross-sectional study with prospective data collection, carried out in hepato-gastroenterology department of the Campus University Teaching hospital of Lomé between July and December 2019, in adult patients hospitalized for liver cirrhosis. Of the 32 patients (men: 62.5%, mean age: 53.3 ± 13.5 years), the main causes of cirrhosis were viral hepatitis (40.6%) and alcoholic cirrhosis (25 %). Cirrhosis was classified Child-Pugh C in 62.5% of patients. The most common electrocardiographic abnormalities were prolonged QTc (59.4%), sinus tachycardia (31,2%), left atrial hypertrophy (25%) and left ventricular hypertrophy (12.5%). The main echocardiographic abnormalities were high cardiac output (68.8%) and left ventricular diastolic dysfunction (56.3%). The diagnostic criteria for cirrhotic cardiomyopathy were met in 37.5% of cases and it was more frequent in Child-Pugh C patients (66.7%) and in cirrhosis of alcoholic etiology (33.4%). Whatever the etiology of cirrhosis, electrocardiographic and echocardiographic abnormalities were common. The prevalence of cirrhotic cardiomyopathy was high, hence the need for systematic cardiological assessment in these patients.
Institutions: University of Lomé, University of Kara
Language: English
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4389688696