Year: 2023
Type: book-chapter
Abstract: The detection of cancerous cells can be possible by single-cell pH sensing and the intracellular pH plays a significant role in the accurate detection of the cancer cells. Fluorescence and functionalized nanoparticle probes are developed for the single pH sensing. The visual pH sensors that are optical chemical pH sensors are very useful for analytical real-time devices and they have many applications in medicine, biology, and the environment. Physiological pH level is an important marker for a variety of biological activities in human tissues. When the pH significantly swerves from this value, the cellular functions are likely to be affected. In diseased tissues, such as tumor, its microenvironment is typically acidic and the confined pH values change to the range of 5.5–7.0 due to their inadequate blood perfusion, hypoxia, and glycolytic cellular metabolism.
Source: Wiley eBooks
Institution: Andhra University
Language: English
Subfield: Analytical Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W4390096512