Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism
Year: 2024
Type: article
Source: Nature Cancer
Authors: Linjie Zhao, Zhixin Qiu, Zhengnan Yang, Lian Xu, Thomas M. Pearce, Qiulian Wu, Kailin Yang, FuLong Li, Olivier Saulnier, Fan Fei, Huaxu Yu, Ryan C. Gimple, Venkateshwari Varadharajan, Juxiu Liu, Liam D. Hendrikse, Vernon Fong, Wei Wang, Jiao Zhang, Deguan Lv, Derrick Lee, Brandon M. Lehrich, Chunyu Jin, Liang Ouyang, Deobrat Dixit, Haoxing Wu, Xiang Wang, Andrew E. Sloan, Xiuxing Wang, Tao Huan, J. Mark Brown, Steven A. Goldman, Michael D. Taylor, Shengtao Zhou, Jeremy N. Rich
Institutions: University of California San Diego, UPMC Hillman Cancer Center, Fudan University, Zhongshan Hospital, State Key Laboratory of Medical Neurobiology, Frontiers Center for Brain Science of the Ministry of Education, Sichuan University, West China Second University Hospital of Sichuan University, State Key Laboratory of Biotherapy, University of Pittsburgh, Cleveland Clinic, Moores Cancer Center, Hospital for Sick Children, University of Electronic Science and Technology of China, Chinese Academy of Sciences, University of British Columbia, Case Western Reserve University, Cleveland Clinic Lerner College of Medicine, University of Toronto, Huzhou Women and Children's Hospital, Howard Hughes Medical Institute, West China Hospital of Sichuan University, West China Medical Center of Sichuan University, Nanjing Medical University, University of Copenhagen, University of Rochester Medicine, University of Rochester, University of Pittsburgh Medical Center
Language: English
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
Open Access status: closed
Funders: U.S. Department of Health and Human Services, National Natural Science Foundation of China, Shanghai Municipal Health Bureau, National Institutes of Health, National Institute on Aging, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Neurological Disorders and Stroke
Awards: Dual Targeting of Brain Tumor Initiating Cells through Inhibition of BMI1 and EZH2 (R01NS103434), G1388891555, G1394932426, Computational Genomic Epidemiology of Cancer (CoGEC) Training Program, G1817963818, G1918981496, Transcriptional Determinants of the Fate Trajectories of Single Human Glial Progenitor Cells in Response to Demyelination in Vivo, G2374862500, G2519406398, G2636359773, G2729832925, G2893523218, G2975286968, G3254086269, G3584110748, G3761224806, G3767908548, G3892622641, Targeting the Circadian Rhythm in Glioblastoma Stem Cells (R01CA238662), G465516749, Targeting brain tumor initiating cell-specific super-enhancer associated genes to treat glioblastoma, G4753498187, G546294159, Metabolic Regulation of Glioblastoma Epitranscriptomics, Cell-intrinsic and contextual determinants of aging by human glial progenitor cells, G6152917131, Epigenetic Regulation of Lipid Metabolism in Glioma Stem Cells, G6412193668, G6597168886, G6704941322, Dynamic Complexity of Brain Tumor Stem Cells (R35CA197718), G7922621378, G8186358050, G8348249257, G8386758852, Metaorganismal Endocrinology in Cardiometabolic Disease
OpenAlex ID: W4390572314