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The dangers of “Chasing the dragon”: a fatal case of heroin-induced leukoencephalopathy

Year: 2023
Type: article
Study design: Case Report
Abstract: Heroin-induced leukoencephalopathy (HLE) is a rare toxic encephalopathy associated primarily with heroin inhalation, commonly referred to as "chasing the dragon." This study presents a clinical case of a 27-year-old polydrug user diagnosed with HLE during hospitalization for rapidly progressive flaccid tetraplegia and aphasia. The clinical manifestations encompassed cerebellar and bulbar dysfunction, coupled with motor impairment and altered consciousness. Based on the clinical data and MRI results, HLE was identified as the most likely cause. This article aims to provide insights into the clinical and radiological aspects of HLE, emphasizing the diagnostic significance of radiological findings. The gold standard examination for diagnosis is MRI, crucial due to the difficulties in obtaining histological confirmation for this rare condition.
Language: English
Field: Medicine
Open Access status: gold
Estimated APC paid: $591
OpenAlex ID: W4390748484
FWCI: 0.162
Cites: 9
Cited by: 1
Related to: 10