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A Case of Acute Eosinophilic Pneumonia Associated With Non-steroidal Anti-inflammatory Drugs

Year: 2024

Type: article

Abstract: Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used and their gastric, cardiovascular, and renal adverse effects have been well documented. Although rare, NSAID-induced acute eosinophilic pneumonia (AEP) may occur. We report a case of AEP related to naproxen and celecoxib. The patient presented with dry cough and breathlessness two weeks after she started taking these drugs. The chest radiograph displayed bilateral opacities and she had peripheral eosinophilia. Bronchoalveolar lavage was performed at a time when blood eosinophilia was already decreasing and cell analysis revealed 63700 cells/mL with 9% eosinophil. After ruling out other possible etiologies, drug-induced AEP was diagnosed. The patient improved after drug discontinuation. When it comes to drug-induced AEP identifying a causative agent is essential as cessation of the drug is the mainstay of the treatment.

Source: Cureus

DOI: 10.7759/cureus.52159

Authors: Rui Ribeiro, Andreia Teixeira, Tânia Lopes, Célia Cruz

Institutions: Hospital de Santo António, Centro Hospitalar do Porto, Hospital de Santa Luzia de Elvas

Language: English

Topic: Eosinophilic Disorders and Syndromes

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4390813836