Evaluating the Immediate Effect of Preextubation Chest Physiotherapy Session on Postextubated Physiological and Diagnostic Cardiorespiratory Parameters in Neonates with Pneumonia: A Randomized Controlled Trial
Year: 2024
Type: article
Abstract: can be lifesaving, they may also induce damage to immature lungs, resulting in adverse acute pulmonary complications and neurodevelopmental outcomes.Therefore, it is crucial to extubate preterm infants from mechanical ventilation as early as possible.However, approximately one-third of preterm newborns are unable to extubate and require continuous respiratory support, such as IntroductIonPneumonia is a common inflammatory lung condition characterized by lung tissue inflammation and fluid accumulation in the alveoli. 1 It poses a significant global health burden, accounting for 10% of all child mortality worldwide and affecting approximately onefourth of all newborns.2 Notably, India has the highest number of newborn pneumonia cases, with an estimated 43 million cases.Neonates differ physiologically from adults, exhibiting increased mucus production and airway obstruction due to narrow airway diameter.Additionally, their weak or absent cough reflex, which is normal for newborns, renders them more vulnerable to pulmonary complications. 3 The risk of pneumonia is closely associated with low birth weight (<1500 gm) and the timing of disease onset (early or late onset), 2,4 with group II Streptococcus being the primary cause during labor, followed by gram-positive and gram-negative bacteria post-birth.Pneumonia is a leading cause of ventilation in term and preterm neonates as decreased oxygenation and excessive secretion production lead to increased airway resistance and complications like atelectasis.Prolonged ventilatory assistance or oxygen support further amplifies the risk of nosocomial infection.4 Although therapeutic oxygen and positive-pressure ventilation
Authors: Vrushali A Ambhore, Manish P Shukla
Institution: MGM Institute of Physiotherapy
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4390948375