A multi-cohort genome-wide association study in African ancestry individuals reveals risk loci for primary open-angle glaucoma
Year: 2024
Type: article
Study design: Observational Study
Source: Cell
Authors: Shefali S. Verma, Harini V. Gudiseva, Venkata R.M. Chavali, Rebecca J. Salowe, Yuki Bradford, Lindsay Guare, Anastasia Lucas, David W. Collins, Vrathasha Vrathasha, Rohini M. Nair, Sonika Rathi, Bingxin Zhao, Jie He, Roy Lee, Selam Zenebe-Gete, Anita S. Bowman, Caitlin P. McHugh, Michael C. Zody, Maxwell Pistilli, Naira Khachatryan, Ebenezer Daniel, Windell Murphy, Jeffrey Henderer, Tyler G. Kinzy, Sudha K. Iyengar, Neal S. Peachey, Kent D. Taylor, Xiuqing Guo, Yii-Der Ida Chen, Linda Zangwill, Christopher Girkin, Radha Ayyagari, Jeffrey Liebmann, Chimd M. Chuka-Okosa, Susan E. Williams, Stephen Akafo, Donald L. Budenz, Olusola O. Olawoye, Michele Ramsay, Adeyinka Ashaye, Onoja M. Akpa, Tin Aung, Janey L. Wiggs, Ahmara G. Ross, Qi N. Cui, Victoria Addis, Amanda Lehman, Eydie Miller-Ellis, Prithvi S. Sankar, Scott M. Williams, Gui-shuang Ying, Jessica Cooke Bailey, Jerome I. Rotter, Robert Weinreb, Chiea Chuen Khor, Michael A. Hauser, Marylyn D. Ritchie, Joan M. O’Brien
Institutions: University of Pennsylvania, New York Genome Center, Temple University, Louis Stokes Cleveland VA Medical Center, Case Western Reserve University, Cleveland Clinic, The Lundquist Institute, Harbor–UCLA Medical Center, University of California San Diego, University of Alabama at Birmingham, Columbia University Irving Medical Center, Columbia University, University of Nigeria, University of the Witwatersrand, University of Ghana, University of North Carolina at Chapel Hill, University of Ibadan, Singapore Eye Research Institute, Massachusetts Eye and Ear Infirmary, Harvard University, East Carolina University, Genome Institute of Singapore, Duke University
Language: English
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Funders: U.S. Department of Veterans Affairs, F. M. Kirby Foundation, Research to Prevent Blindness, Office of Research and Development, University of Pennsylvania, Indiana Clinical and Translational Sciences Institute, Health Services Research and Development, Cleveland Clinic, University of Washington, Case Western Reserve University, Regeneron Pharmaceuticals, James N. Kirby Foundation, Georgia Clinical and Translational Science Alliance, University of Pennsylvania Health System, ONL Therapeutics, Diabetes Research Connection, University of Ibadan, GIGA German Institute of Global and Area Studies, National Institutes of Health, Johnson and Johnson, Department of Genetics, University of Alabama at Birmingham, University of California, Los Angeles, University of California, San Diego, Perelman School of Medicine, University of Pennsylvania, Lerner Research Institute, Cleveland Clinic, National Heart, Lung, and Blood Institute, National Human Genome Research Institute, National Eye Institute, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases, National Center for Advancing Translational Sciences
Awards: G1028935811, G1049558054, G1481755545, G151565447, G1610538956, G164661936, G1718769212, G1765999999, G196819017, G1972786282, G2008237588, G2101559773, G2179675123, G2334180555, G2427874297, G2446180016, G2965656503, G297113894, G3253452452, G3323230809, G343705321, G3692229207, G4132518751, G4429312988, G4539512084, G471519714, African Descent and Glaucoma Evaluation (ADAGES) II: Glaucoma Progression, Diagnostic Innovations in Glaucoma Study (DIGS): Functional Impairment, EYES OF AFRICA : THE GENETICS OF BLINDNESS, G5636261166, G5873106719, G6104092673, G631213127, G6329290396, G6331392353, G6564042377, G6684831006, G7389831629, G7585380919, G781942980, G8217483220, G853874183, G8838742565, G9000003055, G9000008777, G9000013457, G9000026278, G9000031392, G9000037879, G9000043450, G9000095606, G9000098550, G9000100788, G9000140433, G9000162082, G9000174478, G9000229892, G9000256854, G9000316325, Optimizing genetic risk models for primary open-angle glaucoma through expanded population genomic analysis, Primary Open Angle African-American Glaucoma Genetics Study Renewal, Translational Vision Research Training at UCSD, G944134272
OpenAlex ID: W4390972776