Work

Autologous platelet-rich plasma (APRP) in diabetes foot disease: a meta-analysis

Year: 2024

Type: review

Study designs: Systematic Review, Meta-Analysis

Abstract: INTRODUCTION: This study will explore the effectiveness of autologous platelet-rich plasma in the treatment of diabetic foot disease compared to conventional treatments, based on the ulcer healing rate. METHODS: The electronic databases of PubMed, EMBASE, and WOS internet were searched. Evaluated outcome rate of complete ulcer healing. Statistical analysis was performed with RevMan 5.0 software and SPSS 25.0. RESULTS: = 0 %) in growth factors based in autologous platelech-rich plasma (aPRP) group compared with control. Mixed evidence was seen for publication bias, but analyses by using the trim-and-fill method did not appreciably alter results. CONCLUSION: Autologous platelet-rich plasma can improve the complete healing rate of the ulcer compared to current conventional treatments in diabetic foot ulcer patients.

Source: Journal of Diabetes and its Complications

DOI: 10.1016/j.jdiacomp.2024.108690

Authors: Maria Ruiz-Muñoz, Francisco-Javier Martinez-Barrios, Raul Fernandez-Torres, Eva Lopezosa-Reca, Ana Marchena-Rodriguez

Institution: Universidad de Málaga

Language: English

Topic: Diabetic Foot Ulcer Assessment and Management

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,220