Year: 2024
Type: article
Abstract: Fungi have been recognized as a great source of bioactive metabolites with great medical and pharmaceutical applicability. The objective of this work was to produce a fungal extract from Rhizopus spp and identify the secondary metabolites obtained, followed by preparation of a microemulsion formulated with Rhizopus sp extract; characterizing its antioxidant and antimicrobial activity. Among the metabolites obtained, sorbitol, linoleic acid, oleic acid, palmitic acid, and stearic acid stand out. The formulated microemulsion proved to be an effective pharmacological presentation in preserving the metabolites obtained from the fungal extract, and also potentiating in relation to the extract, when comparing the antioxidant activity and antimicrobial action.
Authors: Valéria Maria Sousa Leitão, Marcos Valério Vieira Lyrio, Gabriela Vanini, Carolina Borges Cordeiro, Matheus Filipe Leitão De Oliveira, Matheus Oliveira Do Nascimento, Marcelo Souza De Andrade, André Luis Menezes Carvalho, Arlan Silva Freitas, Wanderson Romão, Flávia Castello Branco Vidal, Amanda Mara Teles, Maria do Desterro Soares Brandão Do Nascimento
Language: English
Subfield: Applied Microbiology and Biotechnology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4392004759