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What is the association of polypharmacy with frailty in heart failure? A systematic review and meta-analysis

Year: 2024
Type: review
Abstract: = 94%, P = 0.01), with a high degree of heterogeneity. However, results were non-significant after adjustment for comorbidity status. Patients with HF and frailty have a higher need of polypharmacy compared to those without frailty, which may increase the risk of potentially inappropriate medications (PIM). Investigating the real-world prevalence of PIM may support clinicians in their routine assessment as part of a comprehensive management strategy in patients with HF and frailty.
DOI: 10.22540/jfsf-09-051
Authors: Konstantinos Prokopidis, Giuseppe Dario Testa, Nicola Veronese, Yannis Dionyssiotis, Joseph McLean, Lauren E. Walker, Rajiv Sankaranarayanan
Institutions: University of Liverpool, Azienda Ospedaliero-Universitaria Careggi, University of Florence, University of Palermo, National Rehabilitation Center EKA, Liverpool University Hospitals NHS Foundation Trust, Liverpool Heart and Chest Hospital
Language: English
Field: Medicine
Open Access status: gold
Estimated APC paid: $161
OpenAlex ID: W4392283705
FWCI: 0.531
Cites: 48
Cited by: 10
Related to: 10