Work

Lactate enhances NMNAT1 lactylation to sustain nuclear NAD+ salvage pathway and promote survival of pancreatic adenocarcinoma cells under glucose-deprived conditions

Year: 2024

Type: article

Source: Cancer Letters

DOI: 10.1016/j.canlet.2024.216806

Authors: Huimin Huang, Shitong Wang, Hongping Xia, Xingling Zhao, Kaiyuan Chen, Guihua Jin, Shipeng Zhou, Zhaoliang Lu, Tongke Chen, Huajun Yu, Xiaoqun Zheng, Haishan Huang, Linhua Lan

Institutions: Wenzhou Medical University, First Affiliated Hospital of Wenzhou Medical University, Zhongda Hospital Southeast University, Southeast University, Guangdong University of Technology

Language: English

Topic: Cancer, Hypoxia, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Wenzhou Medical University, National Natural Science Foundation of China, Wenzhou Municipal Science and Technology Bureau, Natural Science Foundation of Zhejiang Province

OpenAlex ID: W4392655874

FWCI: 12.33

Cites: 55

Cited by: 82

Related to: 10