Flavone Derivatives as Potential Inhibitors of SARS-Cov-2rdrp through Computational Studies
Year: 2023
Type: article
Abstract: The objective of this study is to identify potential targets within the SARS-CoV-2 RdRp for the discovery of novel inhibitors derived from therapeutic natural compounds sourced from aromatic and medicinal plants. In the course of this study, a library was generated containing five naturally occurring flavone derivatives (4a, 4b, 4c, 4d, and 4e) in conjunction with the standard favipiravir-RTP. The compounds underwent an in-silico methodology involving critical steps, including (a) evaluating ADM
DOI: 10.51847/bo9tandz4g
Language: English
Subfield: Drug Discovery
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W4392881024