Level and correlates of physical activity among children and adolescents with juvenile idiopathic arthritis compared to controls: results from a German nationwide prospective observational cohort study
Year: 2024
Type: article
Study design: Observational Study
Abstract: BACKGROUND: Physical active lifestyles are essential throughout growth and maturation and may offer potential preventive and therapeutic benefit in patients with juvenile idiopathic arthritis (JIA). Insufficient physical activity (PA), in contrast, can lead to aggravation of disease-related symptoms. This study aimed to i) examine PA levels in children and adolescents with JIA compared to general population controls and ii) investigate correlates of pronounced physical inactivity in order to identify risk groups for sedentary behaviour. METHODS: Data from children and adolescents with JIA and population controls aged 3 to 17 years documented in the National Pediatric Rheumatologic Database (NPRD) and the German Health Interview and Examination Survey for Children and Adolescents (KiGGS) were used. Self-reported PA was collected from parents/guardians of children up to 11 years of age or adolescents 12 years of age and older. To compare PA-related data, age- and sex-specific pairwise analyses were conducted considering NPRD/KiGGS participants' data from 2017. Correlates of physical inactivity among patients were identified using a linear regression model. RESULTS: Data of 6,297 matched-pairs (mean age 11.2 ± 4.2 years, female 67%, patients' disease duration 4.5 ± 3.7 years, persistent oligoarthritis 43%) were available for evaluation. Almost 36% of patients aged 3-17 years (vs. 20% of controls) achieved the WHO recommended amount of PA, while PA steadily decreased with age (18% of patients aged ≥ 12 years) and varied between JIA categories. Female adolescents and patients with enthesitis-related arthritis were least likely to achieve the minimum recommended level of PA. Physical inactivity was associated with female sex, higher age at disease onset, longer disease duration, more functional disability (C-HAQ) and higher disease activity (cJADAS-10). CONCLUSIONS: Depending on JIA category, children and adolescents with JIA were similarly or even more likely to achieve the WHO recommended minimum level of PA compared to general population controls. However, since a large proportion of young JIA patients appear to be insufficiently physically active, engagement in targeted efforts to promote PA is urgently needed.
Source: Pediatric Rheumatology
Authors: Florian Milatz, Sandra Hansmann, Jens Klotsche, Martina Niewerth, Tilmann Kallinich, Frank Dressler, Johannes-Peter Haas, Rainer Berendes, Gerd Horneff, Markus Hufnagel, Frank Weller-Heinemann, Daniel Windschall, Ralf Trauzeddel, Moritz Klaas, Hermann Girschick, Prasad T. Oommen, Ivan Foeldvari, Serdar Mustafa Cantez, Annette F. Jansson, Matthias Hartmann, Joachim Peitz-Kornbrust, Kirsten Minden
Institutions: Leibniz Association, German Rheumatism Research Centre, University of Tübingen, Humboldt-Universität zu Berlin, Charité – Universitätsmedizin Berlin, Medizinische Hochschule Hannover, German Center for Pediatric and Adolescent Rheumatology, Asklepios Klinik Sankt Augustin, University Hospital Cologne, University of Freiburg, University Medical Center Freiburg, Klinikum Bremen-Mitte, St. Josef-Stift Sendenhorst, Martin Luther University Halle-Wittenberg, Helios Hospital Berlin-Buch, Vivantes Klinikum, Klinikum im Friedrichshain, Düsseldorf University Hospital, Heinrich Heine University Düsseldorf, Schön Klinik Hamburg Eilbek, Universitätsklinikum Gießen und Marburg, Ludwig-Maximilians-Universität München
Language: English
Topic: Physical Activity and Health
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,890
Funders: Pfizer, GlaxoSmithKline foundation, Medizinischen Hochschule Hannover, Humboldt-Universität zu Berlin, Freie Universität Berlin, Universitätsklinikum Köln, Deutsche Kinderrheuma-Stiftung, Robert Koch Institut, AbbVie Deutschland, Novartis Pharma, Chugai Pharmaceutical, Leibniz-Gemeinschaft, Deutsches Rheuma-Forschungszentrum, Leibniz-Gemeinschaft
OpenAlex ID: W4393003045