Year: 2024
Type: article
Study design: Case Report
Abstract: Metaplastic breast carcinoma (MBC) is a rare and aggressive subtype of breast cancer characterized by the presence of both epithelial and mesenchymal components within the tumor. Its clinical and radiological appearance is comparable to other types of breast cancer, but it grows rapidly. The diagnosis of metaplastic carcinoma is largely based on the epithelial origin of the cells confirmed by immunohistochemistry (IHC). Compared to invasive ductal carcinoma, metaplastic carcinoma has a worse overall survival rate. Any patient with a rapidly growing breast mass should be assessed with suspicion of sarcomatoid or metaplastic malignant neoplasm. We report this case due to its rarity and the complex nature of the disease.
Source: Cureus
DOI: 10.7759/cureus.56619
Authors: Vallal Kani, Vimal Chander, Sulochana Sonti, Sridevi Manian, Sudha Vasudevan, Muthuvel Esakki, Sarah Grace Priyadarshini, Karthika Rajendran
Institution: Saveetha University
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4393045309