Prospective surveillance for influenza A virus in Chinese swine farms
Year: 2019
Type: dataset
Abstract: Pork production in China is rapidly increasing and swine production operations are expanding in size and number. However, the biosecurity measures necessary to prevent swine disease transmission, particularly influenza A viruses (IAV) that can be zoonotic, are often inadequate. Despite this risk, few studies have attempted to comprehensively study IAV ecology in swine production settings. Here, we present environmental and animal sampling data collected in the first year of an ongoing five-year prospective epidemiological study to assess IAV ecology as it relates to swine workers, their pigs, and the farm environment. From March 2015 to February 2016, we collected 396 each of environmental swab, water, bioaerosol, and fecal/slurry samples, as well as 3300 pig oral secretion samples from six farms in China. The specimens were tested with molecular assays for IAV. Of these, 46 (11.6%) environmental swab, 235 (7.1%) pig oral secretion, 23 (5.8%) water, 20 (5.1%) bioaerosol, and 19 (4.8%) fecal/slurry specimens were positive for influenza A by qRT-PCR. Risk factors for IAV detection among collected samples were identified using bivariate logistic regression. Overall, these first year data suggest that IAV is quite ubiquitous in the swine production environment and demonstrate an association between the different types of environmental sampling used. Given the mounting evidence that some of these viruses freely move between pigs and swine workers, and that mixing of these viruses can yield progeny viruses with pandemic potential, it seems imperative that routine surveillance for novel IAVs be conducted in commercial swine farms.
Source: Figshare
Institutions: Academy of Military Medical Sciences, Guangdong Medical College, Nantong University, Affiliated Hospital of Guizhou Medical University, Nanjing Medical University, University of Science and Technology of China, Central South University, Anhui Agricultural University, Hong Kong Baptist University, Sun Yat-sen University, Xinjiang Agricultural University, Nanjing Forestry University, Beijing University of Chinese Medicine, Yangtze University, Shanghai Jiao Tong University, Sichuan University, Fudan University, Nanjing General Hospital of Nanjing Military Command, China-Japan Friendship Hospital, First Affiliated Hospital of Xinjiang Medical University, Yale University, Burning Rock Biotech (China), First Affiliated Hospital of Kunming Medical University, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Peking University First Hospital, Henan Provincial People's Hospital, China Academy of Chinese Medical Sciences, Hunan Provincial People's Hospital, Anhui Provincial Children's Hospital, Jiangsu Province Hospital, First Affiliated Hospital of Soochow University, Second Affiliated Hospital of Zhejiang University, Inner Mongolia Medical University, University of Oklahoma Health Sciences Center, Chengdu University of Traditional Chinese Medicine, Tianjin Medical University, Southern Medical University, Shaanxi University of Chinese Medicine, Southeast University, Chongqing Medical University, Tsinghua University, Tufts University, Shandong University, National University of Singapore, Duke University, Duke-NUS Medical School, Duke Kunshan University
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4394559435