Synthetic route design and development for an anthranilic diamide compound containing 2-methyl-2-amino-propanamide group as a potential insecticide
Year: 2024
Type: article
Abstract: This article describes exploration of synthetic strategies and determination of the optimal route for a potential insecticide.The target compound was synthesized through a 5-step process in an overall yield of 73%, which was 4 times that of the original route.Based on the optimization for three key steps, the process was adjusted and shortened, and all the chromatographic purification steps were eliminated.All intermediates and the target compound were obtained by convenient processes with high yields.This economic route featured few side products at each step and mild conditions, providing a highly efficient process for large-scale industrial production.
Source: ARKIVOC
Authors: Junwu Ying, Shuang Liang, Xuesong Li, Gang Wang, Zhongbao Ren, Xiaochen Bai, Jie Lang, Bin Li, Huibin Yang, Haibo Yu
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4394567491