TAVR in Older Adults
Year: 2024
Type: article
Abstract: Calcific aortic stenosis can be considered a model for geriatric cardiovascular conditions due to a confluence of factors. The remarkable technological development of transcatheter aortic valve replacement was studied initially on older adult populations with prohibitive or high-risk for surgical valve replacement. Through these trials, the cardiovascular community has recognized that stratification of these chronologically older adults can be improved incrementally by invoking the concept of frailty and other geriatric risks. Given the complexity of the aging process, stratification by chronological age should only be the initial step but is no longer sufficient to optimally quantify cardiovascular and noncardiovascular risk. In this review, we employ a geriatric cardiology lens to focus on the diagnosis and the comprehensive management of aortic stenosis in older adults to enhance shared decision-making with patients and their families and optimize patient-centered outcomes. Finally, we highlight knowledge gaps that are critical for future areas of study.
Source: JACC Advances
Institutions: Inova Health System, Johns Hopkins University, Johns Hopkins Medicine, University of Washington, VA Puget Sound Health Care System, Veterans Administration, McGill University, Albany Medical College, Brigham and Women's Hospital, VA Boston Healthcare System, New England Geriatric Research Education and Clinical Center, The University of Texas Health Science Center at Houston, University of Michigan, VA Ann Arbor Healthcare System, Ann Arbor VA Medical Center, Columbia University Irving Medical Center, Emory University, Washington University in St. Louis, Harvard University, Hebrew SeniorLife, Santa Clara Valley Medical Center, University of Pittsburgh, Geriatric Research Education and Clinical Center, Kaiser Permanente San Jose Medical Center
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,850
Awards: G1665753110, G1835806896, Kidney Injury in Patients with Acute Decompensated Heart Failure, Frailty and Resiliency in Older Adults with Acute Myocardial Infarction, G3160852588, Nitrite therapy to improve mitochondrial energetics and physical activity in older adults, SCAN-MP (Screening for Cardiac Amyloidosiswith Nuclear imaging in Minority Populations), Modified Application of Cardiac Rehabilitation (CR) for Older Adults (MACRO), G7580998684, Pittsburgh Older Americans Independence Center, PRagmatic EValuation of evENTs And Benefits of Lipid-lowering in oldEr Adults (PREVENTABLE), Improving outcomes from cardiac rehabilitation among older adults through exercise testing and individualized exercise intensity prescriptions, Home-based cardiac rehabilitation using a novel mobile health exercise regimen following transcatheter heart valve interventions (HOME RUN HITTER), Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis, Physical Rehabilitation for Older Patients with Acute HFpEF-The REHAB-HFpEF Trial, Older Americans Independence Center
OpenAlex ID: W4394569714