Work

Antitumor Activity and Synthesis of 1, 2-Disubstituted Benzimidazoles in One-Pot Diverse Using Bismuth (III) Trifluoromethanesulfonate as Catalyst

Year: 2024

Type: article

Abstract: Various 1,2-disubstituted benzimidazoles were synthesized in a facile method using Bismuth(III) trifluoromethanesulfonate. It is suggested that formation of an intermediate between the substrate, amine and solvent gives the N-arylation process. This developed protocol is demonstrated by the efficient reactions involving various substituents ranging from electron-withdrawing groups to electron-donating groups.

Source: Asian Journal of Pharmaceutical Research and Development

DOI: 10.22270/ajprd.v12i1.1358

Authors: A Venkateswarlu, M Harikrishna, P. Thriveni

Institution: Vikrama Simhapuri University

Language: English

Topic: Heterocyclic Compound Synthesis and Bioactivity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

OpenAlex ID: W4395092730

FWCI:

Cites: 1

Cited by:

Related to: 10