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Discovery of Selective Proteolysis-Targeting Chimera Degraders Targeting PTP1B as Long-Term Hypoglycemic Agents

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Year: 2024
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.4c00356
Authors: Zunhua Yang, Yuqi Ying, Shaobing Cheng, Jiamin Wu, Ziwei Zhang, Pei Hu, Jian Xiong, Huilan Li, Qing Zeng, Zhifang Cai, Yulin Feng, Yuanying Fang
Institution: Jiangxi University of Traditional Chinese Medicine
Language: English

Topic: Protein Degradation and Inhibitors
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Jiangxi Provincial Department of Science and Technology, Jiangxi University of Traditional Chinese Medicine
Awards: G5381116219, G568143951, G5851736556, G642805936, G7245905799, G8370886027
OpenAlex ID: W4396554659
FWCI: 2.417
Cites: 40
Cited by: 21
Related to: 10
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