Correlation of Disease Severity with High-Resolution Computed Tomography (HRCT) Severity Scores in COVID-19 Patients - A Cross-Sectional Study
Year: 2024
Type: article
Study design: Observational Study
Abstract: Objective: To determine the relationship of High-Resolution Computed Tomography Chest Severity Scores with disease severity in COVID-19 patients.Study Design: Cross-sectional study.Place and Duration of Study: Pak-Emirates Military Hospital, Rawalpindi Pakistan, from Oct to Dec 2021.Methodology: The study included 173 symptomatic patients with positive COVID polymerase chain reaction. All patients underwent high-resolution computed tomography chest scans and were given severity scores (from 0 to 40) based on the number of lung segments involved. Disease severity was assessed based on oxygen saturation at room air, C-reactive protein levels, and morality on the 21st day. High-resolution chest computed tomography scores were compared with parameters of disease severity.Results: Out of a total of 173 patients, 139(80%) were male, and 34(20%) were female, with a mean age of 62.79±13.87 years (17-92 years). Chest computed tomography severity scores were positively correlated with C-reactive protein levels and mortality on the 21st day (p<0.001). Oxygen saturation at room air decreased with increased involvement in chest scans.Conclusion: Our data suggested that high-resolution computed tomography scores are highly correlated with disease severity and patient outcomes, particularly mortality, in Coronavirus patients
Authors: Abdul Rehman Azeem Dar, Maira Aleem, Muhammad Zafar Ali Qureshi, Tariq Khan
Institution: National University of Medical Sciences
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4396556098