Work

Targeted inhibition of branched-chain amino acid metabolism drives apoptosis of glioblastoma by facilitating ubiquitin degradation of Mfn2 and oxidative stress

Year: 2024

Type: article

Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

DOI: 10.1016/j.bbadis.2024.167220

Authors: Zhuo Lu, Gui-Feng Sun, Kai-Yi He, Zhen Zhang, Xin-Hao Han, Xin-Hui Qu, Deng-Feng Wan, Dongyuan Yao, Fang-Fang Tou, Xiao-Jian Han, Tao Wang

Institutions: Nanchang University, First Affiliated Hospital of Jiangxi Medical College, First Affiliated Hospital of Nanchang University, Jiangxi Provincial People's Hospital, Nanchang Medical College

Language: English

Topic: Cancer, Hypoxia, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Natural Science Foundation of China, Natural Science Foundation of Jiangxi Province, Education Department of Jiangxi Province, Health Commission of Jiangxi Province

Awards: G1822936524, G307619917, G4167010190, G4894736985, Drp1介导的线粒体分裂与NADPH氧化酶在视网膜蓝光损伤中的作用机制研究, G7173549503, G7403616306, G8730708556

OpenAlex ID: W4396700660

FWCI: 2.827

Cites: 45

Cited by: 21

Related to: 9