Work

In vitro antibacterial activity of sulbactam-durlobactam in combination with other antimicrobial agents against Acinetobacter baumannii-calcoaceticus complex

Year: 2024

Type: article

Abstract: Combinations of the β-lactam/β-lactamase inhibitor sulbactam-durlobactam and seventeen antimicrobial agents were tested against strains of Acinetobacter baumannii in checkerboard assays. Most combinations resulted in indifference with no instances of antagonism. These results suggest sulbactam-durlobactam antibacterial activity against A. baumannii is unlikely to be affected if co-dosed with other antimicrobial agents.

Source: Diagnostic Microbiology and Infectious Disease

DOI: 10.1016/j.diagmicrobio.2024.116344

Authors: Sarah M. McLeod, Nicole M. Carter, Patricia A. Bradford, Alita A. Miller

Institution: Entasis Therapeutics (United States)

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Microbiology (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,190