Work

Drug Reaction with Eosinophilia and Systemic Symptoms Induced by Diosmin and Hesperidin: A Case Report

Year: 2024

Type: article

Abstract: : Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe cutaneous adverse reaction which exhibits a diverse range of presentations. We described a 48-year-old man diagnosed with acute generalized exanthematous pustulosis (AGEP)-like DRESS following the administration of diosmin and hesperidin. To our knowledge, diosmin and hesperidin-induced DRESS are exceptionally rare. This aims to raise awareness of potential severe cutaneous side effects in patients taking these agents. Keywords: chronic venous insufficiency, daflon, facial edema, flavonoid, severe cutaneous adverse reactions

Source: Clinical Cosmetic and Investigational Dermatology

DOI: 10.2147/ccid.s464672

Authors: Pasita Palakornkitti, Teerapong Rattananukrom

Institutions: Mahidol University, Ramathibodi Hospital

Language: English

Topic: Drug-Induced Adverse Reactions

Subfield: Pharmacology (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,836