Work

3D layered co-culture model enhances Trastuzumab Deruxtecan sensitivity and reveals the combined effect with G007-LK in HER2-positive non-small cell lung cancer

Year: 2024

Type: article

Source: Biochemical and Biophysical Research Communications

DOI: 10.1016/j.bbrc.2024.150255

Authors: Akari Shiraishi, Tomoko Oh-hara, Yuki Takahashi, Ken Uchibori, Makoto Nishio, Ryohei Katayama

Institutions: Japanese Foundation For Cancer Research, The University of Tokyo, Toppan (Japan), The Cancer Institute Hospital

Language: English

Topic: Lung Cancer Treatments and Mutations

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Takeda Science Foundation, Nakatomi Foundation, Japan Agency for Medical Research and Development, Ministry of Education, Culture, Sports, Science and Technology, Nippon Foundation, Kobayashi Foundation for Cancer Research, Japan Society for the Promotion of Science, Japan Science and Technology Agency

Awards: G1779040330, Searching druggable target sites by developing refined molecular dynamic simulations, G4356561841, Molecular profiling and elucidation of the mechanism regarding small cell carcinoma transformation in EGFR-positive lung cancer, Analysis of cell survival signals and tumor microenvironment in the drug-tolerant persister cells, G881244322

OpenAlex ID: W4399552199

FWCI: 1.293

Cites: 31

Cited by: 5

Related to: 10