Work

Figure S2 from HDAC6 Inhibition Releases HR23B to Activate Proteasomes, Expand the Tumor Immunopeptidome and Amplify T-cell Antimyeloma Activity

Year: 2024

Type: other

Abstract: Fig. S2. a. Correlation of proteasome ChT-like activity with cell number. Proteasome ChT-like activity was determined with indicated number of RPMI-8226 cells at 24 hrs. b. Correlation of proteasome ChT-like activity with incubation time. Proteasome ChT-like activity was determined with 50,000 RPMI-8226 cells/well at indicated time points. c. Correlation of proteasome ChT-like activity with LLVY-R110 concentration. Proteasome ChT-like activity was determined with 50,000 RPMI-8226 cells/well after 24 h of incubation. d. Effect of DMSO (%) on proteasome activity in three MMCLs.

DOI: 10.1158/2767-9764.26058203

Authors: Priyanka S. Rana, James J. Ignatz-Hoover, Byung-Gyu Kim, Ehsan Malek, Yuriy Federov, Drew Adams, Timothy Chan, James J. Driscoll

Language: English

Topic: Multiple Myeloma Research and Treatments

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4399772012

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