Work

Synthesis and Characterization of N-Unsubstituted 2- and 3-Furanimines

Year: 2024

Type: article

Abstract: N-unsubstituted 2-furanmethanimine and 3-furanmethanimine are the simplest derivatives of an imine family containing numerous drugs. They have been prepared in the gas phase by dehydrocyanation of the corresponding α-aminonitriles, characterized by IR and NMR spectroscopy at low temperature and used in transimination reactions. The kinetic stability of the furanaldimines lies between that of alkylated and arylated derivatives, demonstrating the role played by the substituent. The triethylborane complexes of the aldimines were synthesized by reacting the corresponding nitriles with superhydride.

Source: The Journal of Organic Chemistry

DOI: 10.1021/acs.joc.4c00914

Authors: Amavi Kpoezoun, Houda Gazzeh, Gnon Baba, Jean-Claude Guillemin

Institutions: Centre National de la Recherche Scientifique, Institut des Sciences Chimiques de Rennes, École Nationale Supérieure de Chimie de Rennes, University of Lomé, Université de Rennes

Language: English

Topic: Organoboron and organosilicon chemistry

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: Centre National d’Etudes Spatiales, Centre National de la Recherche Scientifique, Commissariat à l'Énergie Atomique et aux Énergies Alternatives

OpenAlex ID: W4400533418