Work

Development of covalent chemogenetic K2P channel activators

Year: 2024

Type: article

Source: Cell chemical biology

DOI: 10.1016/j.chembiol.2024.06.006

Authors: Parker E. Deal, Haerim Lee, Abhisek Mondal, Marco Lolicato, Philipe Ribeiro Furtado de Mendonça, Holly Black, Seil Jang, Xochina El-Hilali, Clifford Bryant, Ehud Y. Isacoff, Adam R. Renslo, Daniel L. Minor

Institutions: University of California, San Francisco, University of California, Berkeley, Lawrence Berkeley National Laboratory

Language: English

Topic: Ion channel regulation and function

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: New York Stem Cell Foundation, Memorial Sloan-Kettering Cancer Center, Pershing Square Sohn Cancer Research Alliance, National Institutes of Health, University of California, San Francisco, National Heart, Lung, and Blood Institute, National Institute of Mental Health, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Neurological Disorders and Stroke

Awards: G289723095, G3293676929, Conformational mechanisms of mGluR gating and regulation, G3655670592, G4726860248, G4826251518, Voltage Gating Mechanisms, G5586261486, Synaptic to circuit homeostasis in the Drosophila locomotor system, Expanding the Chemical Biology of K2P Channels with Selective Cellular and In vivo Probes, Molecular and Cellular Basis of Cardiovascular Disease, Cancer Center Support Grant, Genetic and chemical biological studies of K2P structure, function, andmodulation

OpenAlex ID: W4400769312

FWCI: 1.538

Cites: 85

Cited by: 13

Related to: 10