Work

Synthesis, characterization and biological research of novel 2-(quinoline-4-carbonyl)hydrazide-acrylamide hybrids as potential anticancer agents on MCF-7 breast carcinoma cells by targeting EGFR-TK

Year: 2024

Type: article

Abstract: A sequence of novel 2-(quinoline-4-carbonyl)hydrazide scaffolds carrying the acrylamide moiety have been synthesized and evaluated for in vitro cytotoxicity against an MCF-7 breast cancer cell line.

Source: RSC Advances

DOI: 10.1039/d4ra03963g

Authors: Hany M. Abd El-Lateef, Duaa Bafail, Noura Hamdi Yousef Alhalees, Eslam E. M. Toson, Ali H. Abu Almaaty, Elsherbiny H. Elsayed, Islam Zaki, Magdy M. Youssef

Institutions: King Faisal University, Sohag University, King Abdulaziz University, Ministry of Health, Port Said University, Mansoura University

Language: English

Topic: Synthesis and biological activity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,042

Funder: King Faisal University

OpenAlex ID: W4401034176

FWCI: 1.412

Cites: 42

Cited by: 10

Related to: 10