Gastroesophageal Reflux Disease: Epidemiology, Pathogenesis and Therapeutic Approaches
Year: 2024
Type: article
Abstract: Gastroesophageal reflux disease (GERD) is a disorder that is characterized by upward flux of gastric chyme into the oesophagus. It may happen with no erosion as retrograde flow disorder or can cause erosive esophagitis. It has impact on quality of life of patients causing health and social problems and is correlated with a high risk of malignant esophageal tumor, columnar-lined esophagus, esophageal narrowing and stenosis, and inflammation of esophagus. Genetic predisposition, cigarrete smoking, and obesity, bad lifestyle are considered as risk factors for causing GERD. Classical GERD symptoms are usually clear to reach the accurate diagnosis, but less frequent symptoms and signs, such as chronic coughing and dysphagia, may also happen. Lifestyle management, antacid therapy, and surgical procedures are the major treatment strategies for GERD.
Institution: University of Kufa
Language: English
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4401034234