Work

Case Report: An unusual case of severe autoimmune hemolytic anemia in untreated hepatitis C viral infection

Year: 2024

Type: article

Abstract: Patients with hepatitis C share a variety of anemia, including bleeding, nutritional deficiencies, and anemia of chronic disease. Autoimmune hemolytic anemia (AIHA) is usually reported with interferon-alpha and/or ribavirin treatment in hepatitis C virus (HCV) infections. We report an unusual case of AIHA occurring in a49-year-old patient with untreated hepatitis C infection who presented with functional anemia syndrome. Monospecific direct antiglobulin test showed the presence of anti-complement (C3d++). Cold agglutinin titer was 1/16 at 4°C. The patient improved following blood transfusion, steroid therapy and direct acting antivirals.

Source: F1000Research

DOI: 10.12688/f1000research.148607.1

Authors: H Debbabi, A Chakroun, H Elloumi, H Yacoub, S Ben Azouz, R Marouani

Institution: Hôpital La Rabta

Language: English

Topic: Blood groups and transfusion

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,350