Work

New Interpretations for Sprouting, Intussusception, Ansiform, and Coalescent Types of Angiogenesis

Year: 2024

Type: review

Abstract: Angiogenesis, or the development of blood vessels by growing from already-formed vessels, is observed in embryonic development, physiological cyclical processes such as wound healing, the encapsulation of foreign bodies, tumor growth, and some other situations. In this review, we analyze the cellular mechanisms of angiogenesis, namely, angiogenesis by sprouting, ansiform (by loop formation) angiogenesis, coalescent angiogenesis, and angiogenesis by intussusception (splitting the capillary into two channels). The analysis of data revealed a lot of unanswered questions and contradictions. Here, we propose several new models of angiogenesis explaining these contradictions.

Source: International Journal of Molecular Sciences

DOI: 10.3390/ijms25168575

Authors: Alexander V. Korablev, Irina S. Sesorova, Vitaly V. Sesorov, Pavel S. Vavilov, Anna Mironov, Anna V. Zaitseva, Eugeny V. Bedyaev, Alexander A. Mironov

Institutions: Yaroslavl State Medical Academy, Ivanovo State Medical Academy, University of Milan, Luigi Sacco Hospital, IFOM, Saint Petersburg State Pediatric Medical University

Language: English

Topic: Angiogenesis and VEGF in Cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $3,296

OpenAlex ID: W4401360253

FWCI: 0.259

Cites: 70

Cited by: 7

Related to: 10