Work

Association between single nucleotide polymorphisms of interleukin-35 genes and atopic dermatitis

Year: 2024

Type: article

Abstract: Introduction: The pathogenesis of atopic dermatitis (AD) involves complex interactions between environmental factors, the skin microbiome, epidermal barrier defects, and altered immune responses that develop on a not fully understood specific genetic background. Aim: were selected. Material and methods: Blood samples were collected from 202 AD patients and 178 healthy individuals. SNPs in IL-35 genes were analysed by the polymerase chain reaction with sequence-specific primers (SSP-PCR) method. Results: = 0.02). Conclusions: IL-35 genetic variations appear to play a role in AD pathogenesis.

Source: Advances in Dermatology and Allergology

DOI: 10.5114/ada.2024.141783

Authors: Weronika Zysk, Jolanta Gleń, Monika Zabłotna, Roman Nowicki, Magdalena Trzeciak

Institution: Gdańsk Medical University

Language: English

Topic: Dermatology and Skin Diseases

Subfield: Dermatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $472