Work

Gabriel Synthesis of Aminomethyl-Bicyclo[1.1.0]butanes

Year: 2024

Type: preprint

Abstract: The reaction of iodo-bicyclo[1.1.1]pentanes with potassium phthalimide yields phthalimide-substituted bicyclo[1.1.0]butanes (BCBs), which upon hydrazinolysis afford the corresponding aminomethyl-BCB products.

Source: ChemRxiv

DOI: 10.26434/chemrxiv-2024-8xc0d

Authors: Manivel Pitchai, Nanjundaswamy K.C., Sankar Ulaganathan, Mohammad Javeed, Pavan Srinivas, Sourav Roy, Sarah Traeger, James Mignone, Elizabeth Jurica, Kumar Pabbisetty, Muthalagu Vetrichelvan, Anuradha Gupta, Arvind Mathur, Michael Mandler

Institutions: Biocon (India), Bristol-Myers Squibb (United States)

Language: English

Topic: Organic Chemistry Synthesis Methods

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

OpenAlex ID: W4401423615

Cites: 23

Cited by:

Related to: 10