Year: 2024
Type: article
Abstract: myocyte.Troponin leak happens due to cellular injury to myocardial cells, but the mechanisms involved can differ.5 Three types of pathological mechanisms have been described for myocardial injury: Type 1-atherosclerotic coronary artery disease; type 2-oxygen demand-supply mismatch; and type 3-noncardiac causes.6 Many noncardiac conditions (unrelated to coronary artery disease) such as chronic renal failure, intracerebral pathology, and sepsis can also cause elevated troponin levels.Cardiac dysfunction is a common in sepsis.7 Hence, interpretation of the results should be correlated with the clinical condition. Brain Natriuretic Peptides (NT-ProBNP/BNP)Increased myocardial wall stress can produce high levels of NT-proBNP and BNP.It can help clinicians' diagnosis of acute decompensated heart failure (ADHF) as well as prognostication.Most of the data available are in the nonsurgical patients.8 In critical care, high BNP is seen in patients who had ventricular dysfunction with sepsis-associated cardiomyopathy.9 Even though echocardiography can help to categorize responders or nonresponders for volume challenge, there are no other markers for congestion (pulmonary or systemic).NT-proBNP TroponinTroponins are the common biomarker routinely used in cardiology practice.Cardiac troponins I and troponin T are part of the cardiac
Source: Journal of Acute Care
Author: Padmakumar V Arayamparambil
Institutions: Fortis Hospital, Fortis Hospital
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4401856463