Work

Lipid nanoparticles for enhancing oral bioavailability

Year: 2024

Type: review

Abstract: a selective lymphatic pathway. This review mainly focuses on providing a brief update on lipid nanoparticles (LNPs) that synergistically increase the bioavailability of limited permeable drugs and highlight the transversal mechanisms of LNPs across the gastrointestinal hurdles, transmembrane absorption, transport kinetics, and computational tools. Finally, the present hurdles and future perspectives of LNPs for oral drug delivery systems are discussed.

Source: Nanoscale

DOI: 10.1039/d4nr01487a

Authors: Anushareddy Gangavarapu, Lillian V. Tapia-Lopez, Barnali Sarkar, Jaqueline Pena-Zacarias, Abu Zayed Md Badruddoza, Md Nurunnabi

Institutions: University of Mississippi, The University of Texas at El Paso, Pfizer (United States)

Language: English

Topic: Drug Solubulity and Delivery Systems

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4401995339

FWCI: 2.63

Cites: 117

Cited by: 81

Related to: 10