Supplementary Figure 3 from IFNγ Production by Functionally Reprogrammed Tregs Promotes Antitumor Efficacy of OX40/CD137 Bispecific Agonist Therapy
Year: 2024
Type: supplementary-materials
Abstract: Supplementary Figure 3: Increased IL-2 expression by conventional CD4+ and CD8+ T cells with FS120m treatment. Representative plots (left) and replicate measurements (right) of IL-2+ CD4+ Tconv cells and CD8+ T cells in the spleen and draining lymph nodes on day 18 post tumor implantation. *** P ≤ 0.001, **** P ≤ 0.0001. Unpaired Student’s t test. Bars and error are mean and s.e.m.
Authors: Charlotte J. Imianowski, Paula Kuo, Sarah K. Whiteside, Teresa von Linde, Alexander J. Wesolowski, Alberto G. Conti, Alexander C. Evans, Tarrion Baird, Benjamin I. Morris, Nicole E. Fletcher, Jie Yang, Edmund Poon, Matthew A. Lakins, Masahiro Yamamoto, Neil Brewis, Michelle Morrow, Rahul Roychoudhuri
Language: English
Topic: T-cell and B-cell Immunology
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4402575140