Year: 2024
Type: article
Abstract: Recently, issues of technogenic and environmental safety have come to the fore in the development of civilization. Currently, there is a tendency to increase the number of man-made emergencies. One of the ways to mitigate their impact and consequences on the population is the creation of innovative medical materials. Therefore, the idea of developing a non-toxic, antibacterial and antiviral polymer hydrogel with given functional properties as a wound dressing is relevant today. The work is devoted to the creation of silver-containing gel materials based on polyvinyl alcohol and polyethylene glycol. Hydrogel nanocomposite materials were obtained by reduction of silver ions with the help of ascorbic acid followed by cross-linking of polymer macromolecules by irradiation with a high-energy electron beam. The structure of hydrogel materials was studied by the method of wide-angle X-ray scattering and the presence of metallic silver in the studied polymer systems was confirmed. It was established that polymeric hydrogel materials PVA-PEG-1%-Ag exhibit antimicrobial and antiviral activity. It was found that the investigated polymer hydrogel materials with silver nanoparticles do not exhibit a toxic effect.
Authors: Valerii Demchenko, Svitlana Zahorodnia, Nataliia Rybalchenko, Liubov Artiukh, Polina Zaremba, Maksym Yurzhenko, Illia Sytnyk, Viktoriya Ovsyankina, Volodymyr Neimash
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4402996751