Persistent SARS-CoV-2 infection resolved after B-cell recovery in a patient with follicular lymphoma treated with B-cell depletion therapy
Year: 2024
Type: article
Study design: Case Report
Abstract: A 68-year-old woman with follicular lymphoma was treated with chemotherapy, including the anti-CD20 monoclonal antibody obinutuzumab, and achieved remission. A month after the administration of obinutuzumab, the patient contracted coronavirus disease 2019 (COVID-19), and various antiviral drugs were administered. However, the infection had not been eliminated. One year and three months after chemotherapy, peripheral B cell recovery was achieved, and the infection had resolved. This report provides insight into the course of COVID-19 in patients with impaired humoral immunity.
Authors: Yuriko Sueda, Hirokazu Tokuyasu, Momoka Atsuta, Hiromitsu Sakai, Katsunori Arai, Chika Esumi, Misato Mochizuki, Tomoki Itohara, Naoki Fujisawa, Akira Yamasaki
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,200
OpenAlex ID: W4403522667