The Oxente Chagas Bahia Project: evaluating the efficacy of a rapid diagnostic test and treatments for Chagas disease
Year: 2024
Type: article
Abstract: Chagas disease (CD), caused by Trypanosoma cruzi, is a life-threatening neglected anthropozoonosis primarily transmitted by triatomine bugs. Affecting an estimated 5.7 million people globally, CD has significant morbidity and mortality, particularly in Latin America. The Oxente Chagas Bahia Project aims to screen approximately 30,000 individuals, validate a rapid diagnostic test in a real-world setting, and provide crucial data on its diagnostic performance and cost-effectiveness. Additionally, a biobank will be established to support further research on disease biomarkers and treatment cure rates. By enhancing access to timely diagnosis and treatment, the project will evaluate a strategy to reduce the CD burden.
Authors: Fred Luciano Neves Santos, Tycha Bianca Sabaini Pavan, Cristiane Siqueira Valle, Daniel Dias Sampaio, Larissa Carvalho Medrado Vasconcelos, Maria Hermoso Cristóbal, Ângelo Antônio Oliveira Silva, Cátia Martins de Oliveira, Raquel Santos de Souza, Carmen Nila Phang Romero Casas, André Daher, Isadora Cristina de Siqueira
Institution: Fundação Oswaldo Cruz
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
Awards: G500531620, G8164097464
OpenAlex ID: W4403769857