Profile of Positive Specific Immunoglobulin E (IgE) in Children Tested for Aeroallergens
Year: 2024
Type: article
Study design: Observational Study
Abstract: Aeroallergens are various airborne substances or inhalants, such as pollens, spores, and other. The prevalence of aeroallergens is quite variable from one region or country to another. Objectives: This study is aimed at study profile of positive specific Immunoglobulin E (IgE) test to aeroallergens in Sudanese patients at Al-Rayan laboratory, Khartoum from January 2018 to December 2020. Methodology: A cross sectional study was conducted in -Rayan laboratory in Khartoum state Sudan from 1st of January 2018 to 30th December 2020 among children with positive specific IgE test for aeroallergens. Total coverage of all children with positive specific IgE test for aeroallergens was done. All records with positive specific IgE to aeroallergens have been collected. The aeroallergens were compared to age, gender, and at which time year reach its peak. The positivity of result depends on the antibody detection and its titer. Statistically significant data were analyzed by computer using SPSS program of P-value of equal or less than 0.05. Result: The study included 58 participants. Males were more prevalent (63.8%), and female were (36.2%). The most common affected age was school age. The most prevalent aeroallergen was alder which was positive in all patients, Timothy grass which was positive among (56.9%) followed by cultivated rye, common ragweed and oak. The sensitivity test was positive in (34.5%) of the patients for cockroach, in (27.6%) for cats, in (15.5%) for horses, in (8.6%) for dogs, and in (8.6%) for camels. Months in which aeroallergens were more prevalent were July & December 2018, October of 2019 and October & November of 2020. Conclusion: This study demonstrates that the most common affected age group was school age and the most common aeroallergens were alder, timothy grass and cultivated rye fallowed by common ragweed and oak. There is no statistically significant relation between the patient’s age gender and test months for the tested animals, fungi, trees, grass, and house dust mites.
Language: English
Subfield: Immunology and Allergy
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4404017635