Effect of house dust mite sublingual immunotherapy in patients with adult atopic dermatitis with rhinitis
Year: 2024
Type: article
Study design: Clinical Trial
Abstract: Aim: Whether house dust mite (HDM) sublingual immunotherapy (SLIT) is effective for the skin symptoms of adult atopic dermatitis (AD) is unclear.Methods: HDM SLIT was added to conventional AD treatment for 10 HDM-sensitized AD patients with rhinitis for 2 years.Results: Seven out of ten enrolled patients completed the study. Eczema Area and Severity Index score was significantly reduced when comparing before treatment and at 24 months follow-up. CD203c ratio in the basophil activation test using HDM extract, skin prick test with HDM extract and Dermatophagoides pteronyssinus/Dermatophagoides farinae specific-IgG4 tended to improve when comparing before treatment and after treatment.Conclusion: HDM SLIT might be a therapeutic option for AD patients with rhinitis who are sensitized to HDM.
Source: Future Science OA
Language: English
Subfield: Immunology and Allergy
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,165
OpenAlex ID: W4404342001