Year: 2024
Type: book-chapter
Abstract: The chapter provides a comprehensive overview of the relationship between oxidative stress and the aging process. Oxidative stress arises from an imbalance between the production of Reactive Oxygen Species (ROS) and the body's antioxidant defense system. The mechanisms of action of antioxidants are explored, including enzymatic and non-enzymatic antioxidants, metal-binding proteins, dietary sources, and nutritional supplements. The chapter also delves into the role of oxidative stress in cellular senescence and the aging process. Furthermore, the effectiveness of nutritional supplements in combating aging is examined. The chapter also highlights the impact of oxidative stress on skin health and aging, and discusses the use of topical antioxidants and anti-aging cosmetics. Lifestyle factors such as exercise, stress, sleep, smoking, and alcohol consumption are also explored as contributors to diminished antioxidant defense. The chapter concludes with a discussion on the potential for personalized antioxidant interventions and the development of novel compounds from plants, marine, microorganisms, and synthetic sources for future antioxidant research. Overall, this chapter provides valuable insights into the mechanisms of oxidative stress and the potential of antioxidant interventions in promoting healthy aging.
Source: Antioxidants
Language: English
Subfield: Biochemistry (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,296
OpenAlex ID: W4404476211