Year: 2024
Type: review
Abstract: It is important to understand the effects of environmental factors such as air pollution on mitochondrial structure and function, especially when these changes increase cardiovascular disease risk. Although lifestyle choices directly determine many mitochondrial diseases, increasingly, it is becoming clear that the structure and function of mitochondria may be affected by pollutants found in the atmosphere (e.g., gases, pesticides herbicide aerosols, or microparticles). To date, the role of such agents on mitochondria and the potential impact on cardiovascular fitness is neglected. Here we offer a review of airborne stressors and pollutants, that may contribute to impairments in mitochondrial function and structure to cause heart disease.
Source: Physiological Reports
DOI: 10.14814/phy2.70118
Language: English
Subfield: Health, Toxicology and Mutagenesis
Field: Environmental Science
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $1,950
Funders: Burroughs Wellcome Fund, American Heart Association, Vanderbilt University, Chan Zuckerberg Initiative, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences, United Negro College Fund
Awards: G2393974219, G3274375989, Role of Salt, Isoketal-modified Proteins and Dendritic Cells in Hypertension, G4084644965, G5656976469, G7531705775, PRIDE-Functional and Translational Genomics of Blood Disorders, Deep phenotypic and functional characterization of salt-responsive immune cells in human salt senstive hypertension using CTE-seq, The Meharry Research Training Initiative, G9000052735, ENaC regulation and its role in blood pressure homeostasis, Immune Mechanisms of Salt-Sensitive hypertension
OpenAlex ID: W4404512922