Rio Mamore Hantavirus Endemicity, Peruvian Amazon, 2020
Year: 2024
Type: article
Study design: Observational Study
Abstract: copies/mL). High genomic sequence identity of 87.0%-94.8% and phylogenetic common ancestry with a rodent-associated Rio Mamore hantavirus from Loreto in 1996 indicated endemicity. In 832 samples from Loreto, hantavirus incidence based on IgM ELISA of pooled Sin Nombre (SNV) and Andes virus (ANDV) nucleoproteins and immunofluorescence assay-based end-point titration using SNV/ANDV/Hantaan/Puumala/Saarema/Dobrava/Seoul hantaviruses was 0.5%. Across 3 ecologically distinct departments in Peru, SNV/ANDV IgG ELISA/IFA-based reactivity was 1.7%, suggesting circulation of antigenically distinct New World hantaviruses. Testing for arboviruses, nonendemic pathogens, and antigen-free ELISA corroborated nonspecific reactivity in 2 IgG and several IgM ELISA-positive serum samples. Hantavirus diagnostics and surveillance should be strengthened in Peru ad across Latin America.
Source: Emerging infectious diseases
Authors: Marta Piche-Ovares, Maria Paquita García, Andres Moreira-Soto, Maribel Dana Figueroa-Romero, Nancy Susy Merino-Sarmiento, Adolfo Ismael Marcelo-Ñique, Edward Málaga-Trillo, Dora Esther Valencia Manosalva, Miladi Gatty-Nogueira, César Augusto Cabezas Sanchez, Jan Felix Drexler
Language: English
Topic: Viral Infections and Vectors
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4404792166