Health‐related quality of life determinants in Spanish children with eosinophilic esophagitis
Year: 2024
Type: article
Study design: Observational Study
Abstract: OBJECTIVES: To study the health-related quality of life (HRQoL) and its possible determinant factors in Spanish children with eosinophilic esophagitis (EoE) and their parents. METHODS: Multicenter observational cross-sectional study. The Spanish version of the Pediatric Quality of Life Eosinophilic Esophagitis Module was filled out by EoE patients aged 8-18 and their parents. Demographic, psychosocial, and clinical variables were studied. Multiple linear regression was performed to identify related factors of HRQoL. RESULTS: A total of 279 children and their parents participated (72.7% males). 39.1% received swallowed corticosteroids, 35.5% proton pump inhibitors and 16.8% diet. 1.1% received other treatments and 7.5% received no treatment. Poor compliance to treatment was observed in 11.5% and 6.5% of patients were referred to mental health. The Total Scale Scores were 72.71 ± 17.50 and 75.62 ± 16.73 for children and parents, respectively. "Communication" was the dimension with the highest scores (82.14 ± 21.65 and 81.59 ± 24.13) while "Food and Eating" (48.92 ± 32.94 and 62.85 ± 28.78), and "Food Feelings" (53.55 ± 29.96 and 53.95 ± 27.78) had the lower scores. Patients and parents under dietary treatment showed lower scores than those under pharmacological treatment, 65.77 ± 16.96 versus 74.28 ± 16.96, p = 0.001 and 68.33 ± 17.32 versus 77.24 ± 15.97, p = 0.001, respectively. Factors associated with worse HRQoL scores were symptom frequency, diet, food allergies, and the need for mental health assistance. CONCLUSIONS: The HRQoL of children and their parents was "good." However, diet, frequency of symptoms, food allergies, and the need for mental health care were the factors that had a negative impact on HRQoL of children with EoE.
DOI: 10.1002/jpn3.12426
Authors: Ruth García‐Martínez de Bartolomé, Josefa Barrio‐Torres, Tomás Sebastián‐Viana, Víctor Vila‐Miravet, Enrique La Orden‐Izquierdo, Sonia Fernández‐Fernández, Myriam Herrero‐Álvarez, Marta Soria‐López, Gonzalo Botija‐Arcos, Alejandro Rodríguez‐Martínez, Gonzalo Galicia‐Poblet, Alejandro García‐Díaz, Marta Herreros‐Sáenz, Javier Blasco‐Alonso, Gloria Rodrigo‐García, Natalia Alonso‐Pérez, Ana Fernández de Valderrama‐Rodríguez, Noel Oppenau‐López, Begoña Pérez‐Moneo, Sara Feo‐Ortega, Raquel Vecino‐López, Paloma Donado‐Palencia, José Ramón Alberto‐Alonso, Margarita Revenga‐Parra, Helena Lorenzo‐Garrido, Miguel Ángel Carro‐Rodríguez, Luis Grande‐Herrero, Saioa Vicente‐Santamaría, Elena Balmaseda‐Serrano, María Carmen Miranda‐Cid, Jessica Martín‐González, Ruth García‐Romero, Diana García‐Tirado, Jana Rizo‐Pascual, Pedro Alonso‐López, Miriam Blanco‐Rodríguez, Alicia Rendo‐Vázquez, Antonio Millán‐Jiménez, Ana Castro‐Millán, Eduard Bastida‐Ratera, M. Luz Cilleruelo‐Pascual
Institutions: Universidad Rey Juan Carlos, Hospital Universitario de Fuenlabrada, Hospital Sant Joan de Déu Barcelona, Hospital Universitario Severo Ochoa, Hospital Universitario Rey Juan Carlos, Hospital Universitario Fundación Alcorcón, Hospital Universitario Virgen del Rocío, Hospital Universitario de Guadalajara, Hospital Universitario Puerta de Hierro Majadahonda, Hospital Regional Universitario de Málaga, Hospital Universitario de Burgos, Hospital Universitario Infanta Leonor, Hospital General de Tomelloso, Hospital Clínico San Carlos, Hospital General Universitario de Ciudad Real, Hospital Universitario Nuestra Señora de Candelaria, Hospital Universitario Sanitas La Zarzuela, Hospital de Basurto, Hospital Universitario General de Villalba, Hospital Universitario de Getafe, Hospital Universitario Ramón y Cajal, Hospital General Universitario de Albacete, Hospital General Universitario Gregorio Marañón, Hospital Universitario HM Sanchinarro, Hospital Universitario Miguel Servet, Corporació Sanitària Parc Taulí, Hospital Universitario Infanta Sofía, Hospital Clínico Universitario de Valladolid, Hospital Universitario Fundación Jiménez Díaz, Complejo Hospitalario de Ourense, Hospital Universitario de Valme, Hospital Santa Caterina
Language: English
Topic: Eosinophilic Esophagitis
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4405337682